Synthesis and studies N,N’-bis-(4-chlorothiazol-2-yl)-naphtalene-1,3-diamine

Author: elene Katsadze
Co-authors: T.Iashvili, Sh.Samsonyia
Keywords: naphtalene, thiourea, anion binding receptors
Annotation:

Studies of N-aryl-N-benzoyl-thiourea compounds have attracted increasing attention due to their potential use in agriculture for their insecticidal, herbicidal, and pesticidal activities; in medicine for their antibacterial and antimicrobial activities; The bioactivities of many acyl thiourea compounds have a promoting effect on plant growth. Furthermore, aroyl and acyl thiourea derivatives are attractive model compounds for studies in solid-state chemistry due to their tendency to form intra- and intermolecularhydrogen bonds of the N-H proton-donor groups to sulfurand carbonyl oxygen atoms. Recently, among a variety of possible hydrogen bond donor groups, systems employing thiourea moieties have been proven to be very efficient in the design of neutral anion binding receptors. In this work, we present the synthesis (Scheme), of N,N’-bis(thiazol-4-on-2-yl)-naphtalene-1,3-diamine. Scheme We worked out obtaining methods, determined the structure of intermediate and final products, and optimized the reaction conditions